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AKA-131
Lithocholic acid
Cat. No.
AKA-131
CAS No.
434-13-9
MF
C24H40O3
MW
376.5726
Lithocholic acid is a toxic secondary bile acid that can promote intrahepatic cholestasis.
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Technical Data
Description
Storage and Shipping
References
Product Name
Lithocholic acid
CAS No.
434-13-9
MF
C24H40O3
MW
376.5726
Specification
98%
Description
Lithocholic acid is a toxic secondary bile acid that can promote intrahepatic cholestasis. Packing: 1kg/bag; 25kg/drum or as request Availability: In Stock
Storage and Shipping
Store in a cool & dry place, keep away from strong light and heat.
References
[1]. Jenkins, D.J., et al., Effect on blood lipids of very high intakes of fiber in diets low in saturated fat and cholesterol. N Engl J Med, 1993. 329(1): p. 21-6.
[2]. Yang R, et al. Metabolomic analysis of cholestatic liver damage in mice. Food and Chemical Toxicology. 2018 Jul 14;120:253-260.
[3]. Goldberg, A.A., et al., Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells. Oncotarget, 2011. 2(10): p. 761-82.
[4]. Matsubara, T., et al., TGF-beta-SMAD3 signaling mediates hepatic bile acid and phospholipid metabolism following lithocholic acid-induced liver injury. J Lipid Res, 2012. 53(12): p. 2698-707.
[5]. Yu J, et al. Lithocholic acid decreases expression of bile salt export pump through farnesoid X receptor antagonist activity. The Journal of Biological Chemistry. 2002 Aug 30;277(35):31441-7.
[2]. Yang R, et al. Metabolomic analysis of cholestatic liver damage in mice. Food and Chemical Toxicology. 2018 Jul 14;120:253-260.
[3]. Goldberg, A.A., et al., Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells. Oncotarget, 2011. 2(10): p. 761-82.
[4]. Matsubara, T., et al., TGF-beta-SMAD3 signaling mediates hepatic bile acid and phospholipid metabolism following lithocholic acid-induced liver injury. J Lipid Res, 2012. 53(12): p. 2698-707.
[5]. Yu J, et al. Lithocholic acid decreases expression of bile salt export pump through farnesoid X receptor antagonist activity. The Journal of Biological Chemistry. 2002 Aug 30;277(35):31441-7.
Disclaimer
This product is intended solely for scientific research or regulatory filing purposes. We do not provide products or services to individuals, please strictly comply with all applicable laws, regulations, and the committed use. Use for any other purpose is strictly prohibited.
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